MicroFlow Basic Kits

When to Use MicroFlow Which MicroFlow Kit to Use Ordering a Kit Technical Assistance Training Downloads

In Vitro Micronucleus Rat Micronucleus (ICH Validation) Endogenous Mutation Bone Marrow by Flow Cytometry Radiation Damage Detection Collaboration Opportunities

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Automated Scoring by MicroFlow Background of Micronulceus Test Background of Flow Cytometry

When to use In Vitro MN test MicroFlow Method (In Vitro) Cell Lines Supported High Content Analysis

MicroFlow^PLUS Kit

MicroFlow^BASIC Kits (in vivo)

The Litron Advantage is delivered with every kit:

Faster Results	Obtain results from scoring a complete Micronucleus Test in just one day. This is many times faster than the three to six weeks necessary for traditional microscopic methods.
More Data	With the use of a flow cytometer, the MicroFlow process allows a researcher to score samples within a population of 20,000 reticulocytes, versus only 2,000 using traditional microscopic methods. This not only provides much tighter standard deviations, but also more objective data.
Greater Confidence	MicroFlow data is accepted by the US FDA for the mouse micronucleus assay, a test required by regulatory agencies. Additionally, this method addresses all recommendations made by the International Workshop on Genotoxicity Test Procedures (IWGTP), and the most current Organization for Economic Co-Operation and Development (OECD) guidelines regarding micronucleus testing, Guideline 474, indicates that flow cytometry is an acceptable alternative to microscopic evaluation. Litron developed this patented process and routinely analyzes samples from MicroFlow^BASIC kits, so you can feel confident using this proven method.

In Vivo MicroFlow kits contain all of the quality-assured supplies and reagents for you to collect and fix samples. Kits are available for use with a wide range of species, from mouse and rat up to human. Here's what you get, what it does and how your research is improved using MicroFlow^BASIC Kits:

Feature	Function	Benefit
Anticoagulant/Diluent	Prevents blood cells from clotting before fixation.	Allows samples to be fixed up to 6 hours after collection.
Long Term Storage Solution (LTSS)	Provides increased stability of samples.	Allows sample integrity to be maintained during storage and shipping even in the case of temperature fluctuations. Eliminates the need for ultracold methanol and dry ice during shipping.
VWR 15ml conical polypropylene tubes	Stores and protects fixed blood samples.	These tubes are capable of being capped tightly to reduce diffusion of CO₂ into samples. (Note: Other tubes have not been shown to perform adequately.)
Shipping container	Keeps samples cold during shipping.	This kit-supplied container is designed to ensure that fixed samples on dry ice will remain sufficiently cold for 48 to 72 hours.
Large plastic bags	Protects fixed blood samples.	Provides additional protection against CO₂ diffusion into fixed samples during shipment.

When to Use MicroFlow Which MicroFlow Kit to Use Ordering a Kit Technical Assistance Training Downloads

In Vitro Micronucleus Rat Micronucleus (ICH Validation) Endogenous Mutation Bone Marrow by Flow Cytometry Radiation Damage Detection Collaboration Opportunities

What Makes Us Different Opportunities at Litron eNewsletters Contact Us

Automated Scoring by MicroFlow Background of Micronulceus Test Background of Flow Cytometry

When to use In Vitro MN test MicroFlow Method (In Vitro) Cell Lines Supported High Content Analysis Background of Flow Cytometry