EMM Special Issue, Pig-a Mutation
Available for free download
 |
In vivo assessment of Pig-a gene mutation – recent developments and assay validation. Dertinger SD. and Heflich RH. Environmental & Molecular Mutagenesis. 52(9):681–4, 2011 Dec.
|
|
Need and potential value of the Pig-a in vivo mutation assay – A hesi perspective. Schuler, M., Gollapudi, B. B., Thybaud, V. and Kim, J. H. Environmental & Molecular Mutagenesis. 52(9):685-9, 2011 Dec.
|
|
International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories. Dertinger SD. Phonethepswath S. Weller P. Nicolette J. Murray J. Sonders P. Vohr H-W. Shi J. Krsmanovic L. Gleason C. Custer L. Henwood A. Sweder K. Stankowski LF. Roberts DJ. Giddings A. Kenny J. Lynch AM. Defrain C. Nesslany F. van der Leede B-jM. Van Doninck T. Schuermans A. Tanaka K. Hiwata Y. Tajima O. Wilde E. Elhajouji A. Gunther WC. Thiffeault CJ. Shutsky TJ. Fiedler RD. Kimoto T. Bhalli JA. Heflich RH. and MacGregor JT. Environmental & Molecular Mutagenesis. 52(9):690-8, 2011 Dec.
|
|
International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea. Lynch AM. Giddings A. Custer L. Gleason C. Henwood A. Aylott M. Kenny J. Environmental & Molecular Mutagenesis. 52(9):699-710, 2011 Dec.
|
|
Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethyl-nitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies. Shi J. Krsmanovic L. Bruce S. Kelly T. Paranjpe M. Szabo K. Arevalo M. Atta-Safoh S. Debelie F. LaForce MK. Sly J. Springer S. Environmental & Molecular Mutagenesis. 52(9):711–20, 2011 Dec.
|
|
Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea – comparison with other in vivo genotoxicity endpoints. Cammerer Z. Bhalli JA. Cao X. Coffing SL. Dickinson D. Dobo KL. Dobrovolsky VN. Engel M. Fiedler RD. Gunther WC. Heflich RH. Pearce MG. Shaddock JG. Shutsky T. Thiffeault CJ. Schuler M. Environmental & Molecular Mutagenesis. 52(9):721-30, 2011 Dec.
|
|
Report on stage III Pig-a mutation assays using benzo[a]pyrene. Bhalli JA. Shaddock JG. Pearce MG. Dobrovolsky VN. Cao X. Heflich RH. Vohr H-W. Environmental & Molecular Mutagenesis. 52(9):731-7, 2011 Dec.
|
|
Integration of Pig-a, micronucleus, chromosome aberration, and comet assay endpoints in a 28-day rodent toxicity study with 4-nitroquinoline-1-oxide. Stankowski LF. Roberts DJ. Chen H. Lawlor T. McKeon M. Murli H. Thakur A. Xu Y. Environmental & Molecular Mutagenesis. 52(9):738–47, 2011 Dec.
|
|
Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes. Dertinger SD. Phonethepswath S. Weller P. Avlasevich S. Torous DK. Mereness JA. Bryce SM. Bemis JC. Bell S. Portugal S. Aylott M. and MacGregor JT. Environmental & Molecular Mutagenesis. 52(9):748-55, 2011 Dec.
|
|
Simultaneous measurement of benzo[a]-pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in mutaTM mouse. Lemieux CL. Douglas GR. Gingerich J. Phonethepswath S. Torous DK. Dertinger SD. Phillips DH. Arlt VM. and White PA. Environmental & Molecular Mutagenesis. 52(9):756-65, 2011 Dec.
|
|
Other Related Articles
|
Defining EMS and ENU dose-response relationships using the Pig-a mutation assay in rats. Dobo KL. Fiedler RD. Gunther WC. Thiffeault CJ. Cammerer Z. Coffing SL. Shutsky T. Schuler M. Mutation Research. 725(1-2):13-21, 2011 Oct 9.
|
|
When pigs fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis. Dertinger SD. Bryce S. Phonethepswath S. Avlasevich S. Mutation Research. 721(2):163-70, 2011 Apr 3.
|
|
The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment. Dobrovolsky VN. Miura D. Heflich RH. Dertinger SD. Environmental & Molecular Mutagenesis. 51(8-9):825-35, 2010 Oct-Dec.
|
|
Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies. Dertinger SD. Phonethepswath S. Franklin D. Weller P. Torous DK. Bryce SM. Avlasevich S. Bemis JC. Hyrien O. Palis J. MacGregor JT. Toxicological Sciences. 115(2):401-11, 2010 Jun.
|
|
Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens. Phonethepswath S. Franklin D. Torous DK. Bryce SM. Bemis JC. Raja S. Avlasevich S. Weller P. Hyrien O. Palis J. Macgregor JT. Dertinger SD. Toxicological Sciences. 114(1):59-70, 2010 Mar.
|
|
Erythrocyte-based Pig-a gene mutation assay: demonstration of cross-species potential. Phonethepswath S. Bryce SM. Bemis JC. Dertinger SD. Mutation Research. 657(2):122-6, 2008 Dec 8.
|
|
In vivo mutation assay based on the endogenous Pig-a locus. Bryce SM. Bemis JC. Dertinger SD. Environmental & Molecular Mutagenesis. 49(4):256-64, 2008 May.
|
|
