Litron Laboratories  
Litron Laboratories
Red Blood Cells

Safety Evaluation of AIDS Drug in Newborns
Litron's patented MicroFlow technology was used to measure chromosome damage in newborn patients. This is the first time this powerful, efficient process has been used to monitor drug-exposed mother/ newborn pairs. [more info]


Inventor of the Year Award
Litron scientists were honored by the Rochester Intellectual Property Law Association (RIPLA) with the 2007 RIPLA Distinguised Inventor of the Year Award. [more info]


Scientists Receive Tibbetts Award
Small Business Technology Council has awarded its prestigious Tibbetts Award to Litron's Director of Research and Director of Testing. These directors played key roles in the develpment of Litron's MicroFlow Kits. [more info]

Advances in Micronucleus Analysis by Flow Cytometry
Environmental Mutagen Society Workshop, 2007

An extremely well attended event, this workshop brought together noted experts to discuss micronucleus analysis by flow cytometry and present data based on their own research. Speakers included:

  • Dr. James MacGregor, Toxicology Consulting Services
    Due to an unexpected circumstance, Dr. MacGregor was not able to attend this year's meeting. Instead, Dr. Steve Dertinger presented his data and conclusions concerning MicroFlow analysis in the peripheral blood of various species. [more info]

  • Dr. Leslie Recio, Integrated Laboratory Systems
    Flow Cytometry Based Micronucleus Assay as an Investigative Toxicological Tool [more info]

  • Dr. Jack Bishop, National Institute of Environmental Heath Sciences
    Detection of Elevated %MN-RETs in Blood of Infants and Mothers Following Prenatal AZT [more info]

  • Dr. Robert Heflich, National Center for Toxicological Research, US FDA
    Using Flow Cytometry to Measure Micronuclei in Mice Exposed Transplacentally and Neonatally to AZT Other Antiretroviral Agents [more info]

  • Dr. Jeff Bemis, Litron Laboratories
    Micronucleated Reticulocytes: Bridging Preclinical and Clinical Genetox Assessments [more info]

  • Dr. Ronald Fiedler, Pfizer
    Flow Cytometric Analysis of Rat Bone Marrow for Micronuclei using the CD71 MicroFlow Technology [more info]

  • Dr. Jeff Bemis, Litron Laboratories
    In Vitro Micronucleus Analysis by Flow Cytometry [more info]

These excellent presentations illustrated how micronucleated reticulocyte measurements can serve a cross-species role, bridging pre-clinical safety assessments to human exposure scenarios. Overall, the session was considered an engaging and valuable event.

Makoto and Kumiko Hayashi

We would also like to take this opportunity to congratulate one of our colleagues and friends, Dr. Makoto Hayashi. At the EMS meeting in Atlanta, Makoto was the well-deserved recipient of the 2007 Alexander Hollander Award. His significant advances to micronucleus detection throughout his career - especially for his introduction of acridine orange - have been vitally important to the genetic toxicology community. To quote Makoto in his acceptance speech, "Micronucleus Forever!"

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