Winter
2008-2009

Litron's CEO Honored

Carol R. Tometsko, Litron's Chief Executive Officer, was recently honored by the Women's Council, an affiliate of the Rochester Business Council as a 2009 ATHENA Award Finalist. [more info]

MicroFlow on the Road

Following the successful 2008 Japanese Environmental Muta- gen Society (JEMS) meeting, organized by Dr. Makoto Hayashi, BD Biosciences hosted a day-long In Vivo MicroFlow seminar and wet lab at their facility in Tokyo.

Etsuko Ogawa and Hiroko Tomiyama organized the session, with attendees from 9 companies located throughout Japan. In addition to a seminar describing the latest in micronucleus detection in blood samples, a hands-on training session was held. For information on training for the In Vivo and In Vitro MicroFlow methods, contact us for details.

Litron Introduces a "Long Term Solution"
for MicroFlow® Sample Storage

At Litron, we're always looking for ways to help our clients. When we make advances, we're excited to share them with our customers. Several years ago, we added an anti-platelet antibody to our In Vivo MicroFlow kits to help provide more reliable micronucleus data.

Now we've made another significant advance and we are excited to introduce Long Term Storage Solution (LTSS). This will virtually eliminate all problems caused by warming during storage and shipping. This enhancement, in addition to other benefits, make MicroFlow superior to any other product on the market.

Significant Benefits of LTSS
LTSS was initially developed to assist in shipping MicroFlow biological standards to researchers. Use of this reagent eliminates dry ice and methanol, two factors that held up past shipments. LTSS will help ensure samples arrive in good condition and without excessive delays.

Although the samples still require an initial ultracold methanol fixation, they can be moved into LTSS after a few days for long-term storage. Temperature fluctuations do not adversely affect the quality of the samples with LTSS. Our new process helps maintain the FITC labeling of cells when using the MicroFlow method. Researchers using upright freezers as well as those storing samples long-term, will realize significant advantages. Those sending samples to Litron for analyses will be assured that the sample quality will be maintained. New kit users will find our detailed manuals will ease you through these procedures.

Current MicroFlow Users Evaluate LTSS
LTSS samples were tested at Litron under various temperature conditions and performed very well. We also provided both "original" and "LTSS" standards to five current MicroFlow users to perform side-by-side comparisons. In all cases, LTSS standards performed as well, or better.

Now, more than ever, Litron Laboratories has the "solutions" you need for micronucleus analysis.

See Posters of Litron's Technologies at this year's Society of Toxicology (SOT) Annual Meeting, 2009
Baltimore, MD, March 15 - 19, 2009

Booth
For more information or to speak with the scientists who developed these methods, please visit us at booth 2241.

Selected Posters

• Rapid Radiation Exposure Assessment Accomplished via a Hematoxicity Matrix, Jeffrey Bemis, Litron Laboratories, Abstract 539, Poster 514, March 16, 1:00 to 4:30.
• High Content Flow Cytometry-Based Micronucleus Scoring Method is Applicable to Attachment Cell Lines, Jing Shi, BioReliance, Abstract 1081, Poster 240, March 17, 1:00 to 4:30.
• Performance Characteristics of a Miniaturized and Automated In Vitro Micronucleus Assay, Steven Bryce, Litron Laboratories, Abstract 1069, Poster 228, March 17, 1:00 to 4:30.
• Cyclophosphamide and Etoposide Studies Demonstrate the Cross-Species Potential of the Peripheral Blood Micronucleated Reticulocyte Endpoint, Marie McKeon, Covance, Abstract 1068, Poster 227, March 17, 1:00 to 4:30.
• Flow Cytometric Evaluation of Micronucleated Polychromatic Erythrocytes in Bone Marrow and Micronucleated Reticulocytes in Peripheral Blood Following Acute and Repeat Dosing Regimen of Chemicals, Dorothea Torous, Litron Laboratories, Abstract 1083, Poster 242, March 17, 1:00 to 4:30.
• Development of a Cross-Species Mutation Assay Based on the Pig-a Gene, Stephen Dertinger, Litron Laboratories, Abstract 1899, Poster 539, March 18, 1:00 to 4:30.